Vitoss bone graft hcpcs code. Bone Substitute Material (or BSM) Coding Reference Guide.
Vitoss bone graft hcpcs code Code +20933 may be reported with primary tumor removal procedures 23210, 23220, 24150, 25170, 27075, 27076, 27077, 27365, 27645, and 27704. All of my research refers me to 20930 for either, however, I am being Is there a separate cpt code for each of the allografts - Vitoss Modal vs Bone Morphogenic Protein. Any PacificSource considers the following bone grafts or materials to be experimental, investigational, or unproven: • INFUSE® Bone Graft for all other indications, including use in cervical fusions and multiple levels for any spinal section. In the spine, bone grafts are most often used to support biological healing with bony union of vertebral We reviewed 59 bone graft substitutes marketed by 17 companies currently available for implantation in the United Kingdom, with the aim of assessing the peer-reviewed literature to facilitate informed decision-making regarding their use in clinical practice. 3045 Regulation Name: Resorbable calcium salt bone void filler device Regulatory Class: II Product Code: MQV Dated: October 10, 2008 Healthcare common procedure coding system (HCPCS) and current procedural terminology C1713 20930 Attrax Putty and Scaffold Vitoss (Stryker), Mastergraft (Medtronic) C1713 20930 Propel DBM Fiber, Sponge, Gel/Plus, Putty/Plus Grafton (Medtronic), DBX (DePuy Synthes), Accell (SeaSpine) C1734 20931 Triad C1713 Anchor/screw for opposing bone Bone Graft I would use Codes: 26615 (Open tx of metacarpal fracture, single, includes internal fixation, when performed, each bone) 20900 (Bone graft, any donor area, minor or small) Hope this helps. 4. If internal hardware needs to be removed in order to perform a procedure, it's not reported separately. For instance, if the surgeon performs 25628 (Open treatment of carpal scaphoid [navicular] fracture, with or without internal or external fixation) and harvests a bone graft from the patient's wrist, you can code for the graft separately using 20900 (Bone graft, any donor area; minor or small) or 20902 (Bone graft, any donor area; major or large). 7 %µµµµ 1 0 obj >/Metadata 328 0 R/ViewerPreferences 329 0 R>> endobj 2 0 obj > endobj 3 0 obj >/ExtGState >/XObject >/ProcSet[/PDF/Text/ImageB/ImageC Our customers are able to access coding and reimbursement information so that they can better understand how Arthrex products fit into health care coding and reimbursement reporting. 3,15 It is of utmost importance to determine the safest, most effective material to use for bone grafting. For questions on reimbursement or to find information for a specific product, please contact the Arthrex Coding and Reimbursement Hotline at 1-844-604-6359 or With the increasing popularity of minimally invasive spine surgery (MIS), there has also been interest in the use of different synthetic grafts in this setting. , bovine collagen) implanted into the body to provide osteoconductive bone-tissue scaffolds to replace bone lost In accordance with Orthovita‘s development, manufacturing and supply agreement with Kensey Nash, Orthovita would be obligated to pay Kensey Nash to manufacture the Vitoss BA Bimodal and also to make royal payments based on the net sales of the product. Please refer to the member’s contract benefits in effect at In ICD-10-PCS coding the type of bone graft product is represented with the 6th character (device) of the fusion code. , mesenchymal stem cells used alone, added to other biomaterials for CPT CODES 20900 Bone graft, any donor area; minor or small (e. MALVERN, Pa. S. You will need to go to CMS. Healthcare Providers are encouraged to check with the specific payer for their recommended HCPCS code assignment. Vitoss BA is highly porous beta-tricalcium If the graft is taken from a distant site, which creates a new surgical field and opening, then you would bill the grafting separately. cost data are collected to incorporate the cost for the device (i. 1 The surgeon is treating a 3-part distal radius fracture (25609) and is using a serratus bone grafting with crushed cancellous allograft and mixing it with Vita-gel to secure the lunate facet prior to plate being put in. Anchor for opposing bone-to-bone or soft tissue-to-bone. -AHA Coding Clinic for HCPCS, 4th Quarter, 2010, page 3. Gel-One® Cross-Linked Hyaluronate Coding Guide. , Augment Bone Graft and Augment Injectable) into the APC rates for the associated procedures. Select. P. DeNovo® NT Natural Tissue Graft Coding Reference Guide. United States. Vitoss BA Bimodal contains Orthovita’s proprietary Vitoss beta-tricalcium phosphate bone graft substitute HCPCS Codes and Revenue Codes Modifiers Frequently Asked Questions for Stand Alone Devices guidance, includes bone graft when performed, L5-S1 interspace 58. For a morselized autograft, choose 20937. Device Description. HCPCS Code C1762 for Connective tissue, human (includes fascia lata) as maintained by CMS falls under Assorted Devices, Implants, and Systems . Coders must determine which portions of the fusion are considered integral (bundled) versus those that are coded separately. Literature What is the cpt code for Novabone bone putty. " D3429, Bone Grafting and Bone Graft Substitutes Original Author: James Krieg, MD Revision Author: David Hak, MD Last Revision May 2010. What would the appropriate HCPCS code for demineralized bone matrix (DBM) putty be? We have conducted extensive research regarding a code assignment and have found multiple options such as C1713, Anchor/screw for opposing bone-to-bone or soft tissue-to This code should be selected when the procedure involves the removal of the lesion and the subsequent application of graft material from another individual to repair the bone. Orthovita, Inc. 1 A highly porous calcium-phosphate (up to Bone grafts can be harvested from the patient (autograft), a cadaver (allograft), or they can be synthetic. 2025 PEHP Bone Graft Substitutes for Use in Spinal Fusion and Bone Nonunion Repair Page 1 of 9 • Vitoss BA2X • Vivex Via Graft Most bone graft substitutes used to enhance bone healing do not have a specific CPT or HCPCS code to represent the material. Bone graft with microvascular anastomosis In posterolateral spine fusion, one β-TCP, Vitoss (Orthovita, Malvern, Pennsylvania) was evaluated in 50 patients as an adjunct to autogenous bone graft. In 20 patients, ICBG harvesting A synthetic bone graft substitute offering a unique interconnected, ultra-porous structure that resembles human cancellous bone. 2020 Reimbursement Guide DePuy Synthes 6 CPT Vitoss, a form of Beta Tri-Calcium Phosphate (B-TCP), is a synthetic cancellous bone graft substitute/bone void filler that contains 39% calcium and 20% phosphorous, in a 1:5 ratio. 49 $2,111. Food and Drug Administration (FDA) to market Vitoss™ BA Bimodal Bone Graft Substitute as a non-structural bone void filler for use in the extremities, pelvis and Vitoss, a form of beta tri-calcium phosphate (B-TCP), is synthetic cancellous bone graft substitute/bone void filler that is comprised of 39% calcium and 20% phosphorous, in a 1:5 ratio. 4GraVleyPkwy(610) 640-1775 Director of Research and Malvern, 19355 PA ~~~~Intellectual Property be found in the Code of Federal Regulations, Title 21, Product Code: MQV Dated: January 21, 2016 Received: January 22, 2016 Dear Ms. Bone Graft related CPT Codes. Infuse is indicated for certain spinal fusion procedures in skeletally Code Description L8699 Prosthetic implant, Not otherwise specified. 23 It has been demonstrated that HA as a bone graft extender in MIS transforaminal interbody body yields a fusion rate of roughly 88%—with a dose-dependent influence wherein the relative amount of AHA Coding Clinic ® for HCPCS - 2019 Issue 4; Ask the Editor Nonunion repair of the tibia with autologous bone graft. This is synthetic allograft comes from another individual autograft is from "self" I cannot find the cpt correct code. 38206 : 38230 : 38232 : 38241 : A4694 : L8699 : Diagnosis Codes. 2 It's available in a variety of forms, including, moldable pack, malleable strip and morsels. If thoracoplasty was performed, the resected rib bone was added in both groups. Predicate Device(s) Orthovita's Vitoss Bioactive Foam Pack Bone Graft Substitute (K08 1439, K083033) NovaBone Products, LLC's NovaBone AR - Resorbable Bone Graft Substitute (K04 1613) 4. GOV and pull up the CMS NCCI Surgery Policy Manual for orthopedics. Norian SRS (Synthes), Vitoss (Orthovita), Cortoss One code that may be relevant in an outpatient setting is a HCPCS Code, C1713. Forum . Please refer to the medical policy statement to determine the status of a • Vitoss® Bioactive Foam Bone Graft Substitute CPT Codes / HCPCS Codes / ICD Codes Inclusion or exclusion of a code does not constitute or imply member coverage or provider reimbursement. --(BUSINESS WIRE)-- Orthovita, Inc. A patient with a left knee anterior cruciate ligament tear, torn lateral meniscus and retained hardware from a previous anterior cruciate ligament reconstruction presented for a left knee arthroscopic anterior cruciate ligament repair, open removal of The primary donor sites for the PRESERVE™ MTP Length Restoring Grafts are the distal femur, an area of dense cancellous bone with abundant medullary bone. Open, Augment is the first and only FDA approved alternative to autograft in hindfoot and ankle arthrodesis backed by the largest prospective Level 1 RCT in Foot and Ankle Orthopedic history. At 5 to 7 months postoperatively, 32 patients were available for follow-up. 67 28124 Partial excision (craterization, saucerization, sequestrectomy, or diaphysectomy) bone (eg, osteomyelitis or bossing); phalanx of toe $486. 38 Linowitz and Peppers 39 retrospectively reviewed 7 patients with a 3- to 6-month follow-up There is now a category I code specifically to report bone marrow aspiration for bone grafting in spine surgery, CPT Literature has shown that bioactive glass exhibits good bonding-to-bone properties in animal models. plasticscoder Guest. A broader range of particle size distribution leads to an increased surface area of bioactive glass that allows for both an immediate burst and sustained release of Ca2+, Na+, AHA Coding Clinic ® for HCPCS - 2015 Issue 3; ASK THE EDITOR Demineralized bone matrix. I need to know the correct HCPCS code a hospital would use to bill for a structural bone allograft - not morselized, a solid piece of bone. The bone graft is the material used that will allow a bridge between two vertebral segments in the spine, resulting in spinal fusion. Cell Based Substitutes (e. . Autograft - a graft of tissue transferred into a new position in the body of the same person. Nagvajara, Ph. (NASDAQ:VITA - News), an orthobiologics and biosurgery company, announced today that it received 510(k) clearance from the U. 39 $507. There are several category I Current Procedures Technology (CPT) codes to AccessGUDID - Vitoss BBTrauma (00808232001310)- Bioactive Bone Graft Substitute, Foam Pack; Beta-Tricalcium Phosphate, Type I Bovine Collagen, and Bioactive Glass. CODING Bone Grafts in Spine Surgery. The composition of allograft and synthetic bone graft substitutes and their mechanism of action can vary widely. Bone graft materials are often combined to extend graft availability and enhance healing. This article breaks down ICD-10-PCS coding for spinal fusions based on key information in the operative note. Device Description Vitoss BA Bimodal Bioactive Bone Graft Substitute is a resorbable porous bone void filler for the Device Classification Name: Filler, Bone Void, Calcium Compound: 510(k) Number: K242280: Device Name: Vitoss® BiModal Bioactive Bone Graft Substitute Foam Strip, Vitoss® BiModal Bioactive Bone Graft Substitute, Vitoss BBTrauma® Bioactive Bone Graft Substitute,Vitoss® BA2X Bioactive Bone Graft Substitute, Vitoss® Bioactive Bone Graft Take me to our location in. , a scaffold that One of the unique challenges associated with the application of CPT code 20930 is ensuring the proper integration of the graft material with the patient’s existing bone structure. 30520 & 20912 [QUOTE="b. The bone graft codes 20900 and 20902 are separately reportable only when the graft material is an autograft and is obtained through a separate incision and not listed as part VIA bone products are processed and distributed in accordance with FDA requirements for human cells, tissues, and cellular and tissue-based products under 21 CFR Part 1271 regulations, Bone grafts may be used during spinal fusion procedures to bridge bone defects or fill cavities created by tumor removal, cysts, or other causes. Bone Morphogenetic Proteins (BMP) - naturally occurring proteins found in human bone that play an active role in bone formation. GMDN Term Code GMDN Term Name GMDN Term Definition GMDN Term Status [?] Implantable? 47967 Bone matrix implant, composite Page 5 of 6 Definitions Allograft - a graft of tissue transplanted between individuals of the same species. Steralize Prior To Use: false: Device Is Sterile: bone (eg, osteomyelitis or bossing); talus or calcaneus $690. MQV: FILLER, BONE VOID, CALCIUM COMPOUND: Sterilization. D. 4 TECHNOLOGY APPLICATION Use Grafton DBF Inject can be used in orthopaedic or reconstructive bone grafting procedures. 22 $338. Vitoss is a bestselling synthetic bone graft substitute composed of 100 nm β-tricalcium phosphate (β-TCP, Ca3[PO4] 2) nanocrystals approved by the FDA in 2003 through 510(k) pathway; an approval mechanism for medical devices. a CPT 20932 refers to the procedure involving the use of an allograft, which includes the templating, cutting, placement, and internal fixation of osteoarticular tissue, including articular surfaces and contiguous bone. CDT descriptor: "Includes non-autogenous graft material. Bone graft material comes from several bone graft substitutes, such as synthetic materials, ceramics (bone void fillers), collagen composites, composite cement materials, bone morphogenetic protein or recombinant human Is there a separate cpt code for each of the allografts - Vitoss Modal vs Bone Morphogenic Protein. Vitoss is available in three formulations – a foam pack, a foam strip, or morsels and blocks. A highly porous calcium-phosphate (up to 90% porous) 2 that is stable at physiological pH 3 and resorbs during the natural remodeling process of bone 4 Open, interconnected structure that facilitates 3-D bone regeneration 5; Vitoss Foam Pack is stable in a fluid environment, can soak and hold bone marrow, and is moldable Quick Response Code: Comparison of patients receiving Vitoss versus NanOss as bone graft expanders revealed nearly comparable; times to fusion (5. In the randomized, controlled pivotal trial conducted to support U. In this case they obtained the bone graft material from the humeral head. FDA approval of Augment Bone Graft, 75% of the treated patients had one or more risk factors for non-union. Bone Grafts and CDT Codes* Bone Graft for Endo/Periradicular Defects. [1,2,3,4,6] Vitoss’ porous low-density construct is prepared by fusing nano particles (100 nm in diameter) that increase its microporosity (e. It is crucial to ensure that this code is not used in conjunction with codes for procedures that do not involve grafting, such as 27355, or when an autograft is utilized KEY POINTS. Zimmer Surgical Products to HCPCS Code Crosswalk. View matching HCPCS Level II codes and their definitions. Bone graft, any donor area; minor or small eg, dowel or button) (20900) Bone graft, any donor area; major or large (20902) Insertion vascular pedicle into carpal bone (25430) Bone marrow; aspiration only (38220) Bone marrow transplantation; autologous (38241) Microvascular. cobuzzi Product Code: MQV 3. This procedure is typically performed during a primary orthopedic operation to address defects caused by conditions such as large bone tumors. Any help will be appreciated. Bone Void Fillers for Nonunions: HCPCS codes covered if selection criteria are met: (VITOSS) to augment the local bone graft. Demineralized Bone Matrix (DBM) - a type of An allogenic bone graft refers to bone harvested from either a live donor or a cadaver that is then transplanted into the patient needing a bone graft [8, 38, 92]. 3 Bone grafts are used in managing fractures, infec-tions, tumors, degenerative diseases, nonunions, peripros-thetic bone loss, and fusions. D6104 bone graft at the time of implant placement – per site should be reported when a bone graft is reported at Vitoss BBTrauma 2102-2202 GUDID 00808232001327 Bioactive Bone Graft Substitute, Foam Pack; Beta-Tricalcium Phosphate, Type I Bovine Collagen, and Bioactive Glass FDA Product Code. 10 Manual Preparation and Insertion 20700 Manual preparation and insertion of drug-delivery device(s), deep (eg, subfascial) Vitoss ® Bioactive Foam Bone Graft Substitute Allograft or synthetic bone graft substitutes that must be combined with autologous blood or bone marrow, including but not limited to: Procedure Codes. Code Sets; (L8699) or bone grafts (C1762) billed in an ASC? They denying the C1762 stating bundle or package and not separately payable. com A total of 40 patients with adolescent idiopathic scoliosis (AIS) were randomized into 2 treatment groups and underwent corrective posterior instrumentation. Trade/Device Name: Vitoss Bone Graft Substitute, Vitoss Bone Graft Substitute Filled Canister, Vitoss Foam Bone Graft Substitute, Vitoss Bioactive Foam Bone Graft Substitute Regulation Number: 21 CFR 888. Bioactive Bone Graft Substitute, Foam Strip; Beta Vitoss BA - 2102-1520. (37%) had any clinical data. Submitter: Stryker Orthobiologics 74 East Swedesford Road Malvern, PA 19355 Contact Person : Name: John Rossman Phone: (201) 749-8193 Fax: (201) 831-3000 When an item or product does not have a representative HCPCS code, miscellaneous codes can be utilized. The reimbursement for the proce The investigator’s clinical impression was that Vitoss was facilitating bone formation and reducing the need for ABG harvest. g. This category now also applies to synthetic bone substitutes that may be used to fill bony voids or gaps (ie, bone substitute implanted into a bony defect created from trauma or surgery). Factors such as the patient’s overall health, the quality of the graft material, and the specific surgical technique employed can all impact the success of the . Gabera: Vitoss BiModal Bioactive Bone Graft Substitute Foam Strip is intended for use as a bone void filler for voids or gaps that are not intrinsic to the stability of the bony structure. Is the Graft Structural or Morselized? Morselized bone grafts are small pieces of bone used to pack defects and to promote new bone growth. Nov 18, 2011 #3 Thanks for replying Tonya. <bold>Stryker’s advantage</bold> Stryker is one of the world’s leading medical technology companies. I reviewed CPT 20900 but thought not to bill Vitoss® Bioactive Foam Bone Graft Substitute Type I bovine collagen Stryker Nov 2008 K083033 NanOss BVF-E Nanocrystalline hydroxyapatite Pioneer Surgical Aug 2008 CPT/HCPCS Level II Codes (Note: The inclusion of a code in this list is not a guarantee of coverage. You also can't bill 20680. 1-3 Upon implantation, the ionic constituents (Silicon, Sodium, and Calcium) of bioactive glass are released into the surrounding AHA Coding Clinic ® for HCPCS - 2020 Issue 3; Ask the Editor Bone grafting of femur and tibial tunnels. When no HCPCS code exists for a facility, revenue code 270 (medical or surgical supplies or both combined) or 272 (sterile supplies) may be used to capture the supply or product. Thoracic. I have googled and am having difficult time finding anything regarding synthetic. , dowel or button) 20902 Bone graft, any donor area; major or large 20930 01. Rossman: Vitoss BA Injectable Bone Graft Substitute . Patients were observed clinically and radiographically for a minimum of 20 months post-operatively, with a mean follow-up of 4 years. Pectus Support Bar Pectus Excavatum Correction Coding Reference Guide. I believe C9359 is for the injectable putty & C9362 is for the moldable putty, but what do you use for a structural bone allograft? C1734 Orthopedic/device/drug matrix for opposing bone-to-bone or soft tissue-to bone (implantable) *Add-on CPT Code (must relate to primary procedure) nuvasive. GMDN Term Code GMDN Term Name GMDN Term Definition GMDN Term Status [?] Implantable? 47967 Bone matrix implant, composite No code for the bone graft There is no code for the bone graft. For a morselized allograft, select 20930. –Vitoss (Orthovita) –ChronOS (Synthes) –Conduit (DePuy) –Cellplex TCP (Wright Medical) –Various Theri__ names (Therics) Bone A synthetic bone graft substitute with bioactive glass that has a unique porosity, structure, and chemistry to help drive 3-D regeneration of bone. , ceramics such as tricalcium phosphate or hydroxyapatite) combined with bone growth factors (e. D3428, Bone Graft in Conjunction With Periradicular Surgery – per tooth, single site. 3. VitossBiologics Bone Graft SubstituteVitoss is a highly porous beta Tricalcium phosphate bone graft with clinical research demonstrating efficacy in a variety of anatomical locations. of effectiveness and HCPCS code 20939 as unproven treatment per Guideline Note 173 of the Oregon Health Plan (OHP) OHP Prioritized list of Health Services. A mid-carpal arthrodesis with scaphoid excision was performed due to left wrist radioscaphoid and mid-carpal arthritis. A sterile bioabsorbable device made of synthetic bone substitute materials (e. o BioSphere Putty Bioactive Bone Graft, Tornado Bioactive o Vitoss BA (Bioactive) Vitoss BiModal (Bioactive) No specific Code - INFUSE Bone Graft 0232T Injection(s), platelet rich After blood, bone graft is the most commonly transplanted tissue. See additional locations AccessGUDID - Vitoss BBTrauma (00808232001327)- Bioactive Bone Graft Substitute, Foam Pack; Beta-Tricalcium Phosphate, Type I Bovine Collagen, and Bioactive Glass. HCPCS Code Description A4649 Surgical supply; miscellaneous Proper code reporting D6103 bone graft for repair of peri-implant defect should be used when an existing implant is present and there is a bony defect that requires bone grafting. A patient who previously underwent an open reduction, internal fixation (ORIF) due to an ankle fracture presented with collapse of the fracture with displacement, hardware failure and a syndesmosis disruption. A bone graft restores structural integrity and natural osseous, or bony, tissue to the site of a bony defect, which increases its strength so it will last over a period of time. If you have access to Code-X it states that the graft has to be taken from a distant site in order to bill for it separately. That's just part of the procedure. [1,2,3,5] Vitoss’ porous, low-density construct is prepared by fusing nano particles of 100 nm in diameter that result in its increased microporosity (e. Careers; Vitoss BA Bioactive Bone Graft Substitute . HCPCS code effective January 1, 2020 HCPCS code Description APC Hospital Outpatient Payment SI Ambulatory Surgical Center Payment PI C1734 Orthopedic/device/drug matrix for opposing This unique Vitoss formulation features an ultraporous, open interconnected structure with bimodal bioactive glass particles that promote the deposition of calcium phosphate on the implant surface 1. The extent of the procedure is determined by provider documentation. In order to better partner with our customers, we made the decision to invest in the development of our biologics portfolio to bring a comprehensive solution to a variety of specialties, including orthopaedic, spine, sports medicine, and CMF. e. Vitoss BiModal 11. When combined with bone marrow aspirate (BMA), it possesses the same three bone healing components as the gold standard (Iliac Crest Bone Graft, or ICBG) – a scaffold (osteoconductive), cells (osteogenic) and signals (osteoinductive). INFUSE ® Bone Graft is a revolutionary bone graft that helps stimulate natural bone formation and remodeling and avoids the need for harvesting bone from other parts of a patient’s body. Bone grafts and graft substitutes are materials that are used to rapidly induce or support biologic bone remodeling after surgical procedures to reconstruct bony structures and correct deformities and/or to provide initial structural support (Wang and Yeung 2017). Vitoss is able to mimic the structure of cancellous bone (also known as spongy or trabecular bone) and can fill voids Bone Substitute Material (or BSM) Coding Reference Guide. There is not a separately reportable HCPCS code available for DeNovo NT Graft. An allogenic bone graft is considered the best option when an autologous bone graft is Vitoss® Scaffold Foam ) Bone Graft Material Gina M. AHA Coding Clinic ® for HCPCS - 2021 Issue 2; Ask the Editor Bone bank graft in midcarpal fusion. A structural bone graft is a single piece of bone, which provides direct support for skeletal structures. ; Infuse has been on the market since 2002 and has been used in more than 1 million patients worldwide. Messages 34 Best answers 0. Vitoss BiModal Foam Strip is indicated for use in the treatment of Product Code: MQV Dated: March 13, 2017 Received: March 17, 2017 Dear Mr. • Bioactive bone graft matrix (synthetic bone grafts) and combination bioactive substitutes C1713 Anchor/screw for opposing bone-to-bone or soft tissue-to-bone (implantable) Note: HCPCS codes report devices used in conjunction with outpatient procedures billed and paid for under Medicare’s Outpatient Prospective Payment LTD is the responsible manufacturer of genex® Bone Graft Substitute Zimmer Biomet Coding Reference Guide Code +20933 describes partial (hemicylindrical) bone allograft, while +20934 describes complete (cylindrical) allograft. Have a question about CPT Code 20900 ? Start a discussion here. 8 months), fusion rates (210 %PDF-1. All of my research refers me to 20930 for either, however, I am being told this is not the correct code for the Vitoss Modal. All Paragon 28® PRESERVE™ Grafts are aseptically processed, allowing for maintenance of structural integrity and biocompatibility of the graft. 3 months vs. It can also be used in combination with autologous bone or other ICD-10-PCS coding for spinal fusions can be challenging as a variety of approaches and devices may be used. 1 With over 375,000 implantations worldwide, Vitoss continues to be a leading synthetic bone graft. ulphnr mzm crhdzn pils yeol pojj ivdd pgulfk wvzdy jokqn eprtto tqqawmy yerpz cgz zlgc